Spoil his legacy? Like, if someone treads in a huge, perfectly formed, steaming hot dog turd? That kind of spoilt legacy?
And shame? The man is a weapons-grade narcissistic arsehole. He doesn’t know the meaning of the word.
Spoil his legacy? Like, if someone treads in a huge, perfectly formed, steaming hot dog turd? That kind of spoilt legacy?
And shame? The man is a weapons-grade narcissistic arsehole. He doesn’t know the meaning of the word.
You know, you can be a cisgender white male, and still hate Donald Trump.
Still poop. Still poop.
I see you have met my cat
Come on guys, it’s nearly been an hour, we’re starving here.
It took 3 seconds, and it was AI what figured it all out.
Burgers are served on a scaffold board/shovel/roof tile
Coleslaw is always referred to as house 'slaw.
Menu prices omit the $ sign/£ sign.
Eg. Triple cooked fries 4
Holy fuck, that last level! Dude, you have unlocked some deep seated trauma.
The best words
You smooth motherfucker!
IDLES.
T
H
I
C
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Abstract
High protein intake is common in western societies and is often promoted as part of a healthy lifestyle; however, amino-acid-mediated mammalian target of rapamycin (mTOR) signalling in macrophages has been implicated in the pathogenesis of ischaemic cardiovascular disease. In a series of clinical studies on male and female participants (NCT03946774 and NCT03994367) that involved graded amounts of protein ingestion together with detailed plasma amino acid analysis and human monocyte/macrophage experiments, we identify leucine as the key activator of mTOR signalling in macrophages. We describe a threshold effect of high protein intake and circulating leucine on monocytes/macrophages wherein only protein in excess of ∼25 g per meal induces mTOR activation and functional effects. By designing specific diets modified in protein and leucine content representative of the intake in the general population, we confirm this threshold effect in mouse models and find ingestion of protein in excess of ∼22% of dietary energy requirements drives atherosclerosis in male mice. These data demonstrate a mechanistic basis for the adverse impact of excessive dietary protein on cardiovascular risk.
Or OneDrive.
File > Save As > Desktop.
Doesn’t save to local Desktop, but the OneDrive desktop wherever the fuck that is.
Drinks are served in jars, and your fries, well, you get 8 fries in a rusty old can.
Fuck the monarchy. Fucking parasites.
This ain’t your first rodeo, eh?
How do you know?