

Yup, the installation guide says to comment out the things you don’t want to run
I waddled onto the beach and stole found a computer to use.
🍁⚕️ 💽
Note: I’m moderating a handful of communities in more of a caretaker role. If you want to take one on, send me a message and I’ll share more info :)
Yup, the installation guide says to comment out the things you don’t want to run
There’s the good-karma-kit, which is a Docker compose bundle of some popular projects: https://github.com/ArchiveBox/good-karma-kit
It could act as a list to go off of, if you don’t want to host all of them. The link has more info on each, as well as which ones are non-profit / for-profit
Overview
Have some space computing power and want to donate it to a good cause? How about 10+ good causes at once?
♻️ put an under-utilized system to good use
🚲 use as much or as little CPU/RAM/DISK as you want
✨ 100% more soul warming than mining
📈 geek out over your CPU/disk/bandwidth stats on the leaderboardsThis is a collection of containers that all contribute to public-good projects:
- networks: Tor, i2p
- computing: boinc, foldingathome
- archiving: archivewarrior, zimfarm, kiwix, archivebox, pywb
- storage: ipfs, storj, sia, transmission
This v1 list was started by the ArchiveBox project, but it’s open to contributions.
Depending on what restrictions you have, you could try VSCode? That’s what students were told to do at my university for remote C / C++ development off the school’s servers
https://code.visualstudio.com/docs/remote/ssh
I’m not familiar with the others, but for vscode
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in the bottom leftDoesn’t look like there’s a link in the post, you may have missed it?
There are a few selfhosted versions of this.
It can be helpful to reference this info, and if it’s only stored on your computer then I don’t see the downside
Cross posted to [email protected], and looks like someone already shared it on [email protected]
‘upperBalcony’ is assigned a value but never used
Ok but still, what if
math requires it, the risk is just too high
I think the important part is about who is running the server, rather than who made the software
The fediverse is interesting in that context because each instance can decide where they set up the infrastructure or how they process data / requests. The same applies to self hosting
I saw an article that outlined which country each fediverse platform “originated” from, such as Canada for Pixelfed and Germany for Mastodon. That’s fun to know about, but otherwise not important to users compared to the instances themselves
At most it might speak to which laws will govern the project itself, but even then someone can fork a project that goes astray
I think this is being worked on / discussed in the background for how to best implement this. There are a lot of complications when you get into the details of how it should work
In the meantime, another perspective is that even on centralized platforms there will be multiple communities for a particular theme. Especially at first, there may be a few communities for something before one of them will win out as THE community for it.
That’s already happened here for a few communities, where there is ONE main community for a topic.
For others, it’s still in the early stages or (like on Reddit) there are multiple concurrent communities for ideological reasons.
The exception would be if something is created or thought of on the platform, in which case there may only be one community for it from the start. For example, [email protected] was a fun idea that started here and has grown into a solid community now (thanks to @[email protected]’s regular posts 😊).
Patient gets to keep their canine then.
That’s a good point. I remember seeing an article about tooth re-growing teeth (in ferrets), and while I don’t remember if it was stem cells, that might be nicer than having to lose a tooth for an eye.
Do you know if tissue grown from a patient’s own stem cells is generally not rejected by the immune system
My background is a bit limited here, but looking around it seems that it’s ‘better’ but not necessarily ‘rejection proof’
HSCT came to mind first, but those are replicated inside the patient:
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells […] in order to replicate inside a patient and produce additional normal blood cells. HSCT may be autologous (the patient’s own stem cells are used), syngeneic (stem cells from an identical twin), or allogeneic (stem cells from a donor)
Autologous transplants have the advantage of lower risk of infection during the immune-compromised portion of the treatment, since the recovery of immune function is rapid. Also, the incidence of patients experiencing rejection is very rare (and graft-versus-host disease impossible) due to the donor and recipient being the same individual
Induced pluripotent stem cells seem closer:
Since iPSCs can be derived directly from adult tissues, they not only bypass the need for embryos, but can be made in a patient-matched manner, which means that each individual could have their own pluripotent stem cell line. These unlimited supplies of autologous cells could be used to generate transplants without the risk of immune rejection. While the iPSC technology has not yet advanced to a stage where therapeutic transplants have been deemed safe, iPSCs are readily being used in personalized drug discovery efforts and understanding the patient-specific basis of disease.
This other article from 2013 lists a few concerns, and I think this is the closest to what you were looking for: https://pmc.ncbi.nlm.nih.gov/articles/PMC3931018/#sec3
Potential Causes of iPSC Immunogenicity
[…] The first potential cause is immaturity of cells differentiated from iPSCs in vitro. […] There are a number of human cell types that, to date, can be differentiated only to immature phenotypes in vitro […] . An immature phenotype poses two risks for immune response, the first being low MHC class I (MHC-I) expression. Natural killer (NK) cells target cells with low MHC-I levels, and although differentiation of iPSCs causes these levels to rise, they may not reach those of adult tissue. […] Another risk of an immature phenotype is expression of embryonic or fetal proteins. These antigens may not have been present during immune system education to go through negative selection in the thymus, leaving them susceptible to T cell attack. T […].
A second potential cause of iPSC immunogenicity is genetic and epigenetic changes that arise from reprogramming or adaptation to culture conditions. Recent studies have demonstrated that reprogramming to pluripotency is incomplete and that iPSCs carry an epigenetic memory of their tissue of origin that affects gene expression and can restrict differentiation potential (26–30). […]
A third potential cause is culturing of iPSCs, or their differentiated progeny, with xenogeneic or non-physiological culture reagents. […] hESCs take up the non-human sialic acid N-glycolylneuraminic acid (Neu5Gc) from mouse cell feeder layers and animal serum-containing culture media. This represents a risk because humans have circulating antibodies to Neu5Gc (37). Several groups have since developed xeno-free culture conditions for reprogramming and differentiation that reduce or eliminate Neu5Gc expression, although these methods are costly and can be technically challenging (38–40). […]
[…]
A fun fact I came across on that wikipedia article:
Yamanaka named iPSCs with a lower case “i” due to the popularity of the iPod and other products.
See the crosspost where someone commented a summary of the procedure
I have only tried Zen from your list and it’s been nice so far. The most recent update last night broke something with the multi account containers, but other than that it’s been smooth sailing for months.
Ladybird looks promising but it’s not out yet. Planning to try switching to it when it’s out.
Arc is apparently dead (or dying), but it was chromium based, VC funded, and Zen does most of the same things anyway. https://www.theverge.com/2024/10/24/24279020/browser-company-ai-browser-arc
The UI mostly, and because the layout is familiar to them
I installed OnlyOffice for a family member and they have no complaints. They were happy to learn they don’t need to worry about subscriptions anymore either
I haven’t seen this application yet, but is the difference that you can install word locally instead of using it in a web browser?
Did smarttube have custom feeds? I only saw playlists (where you add videos to them manually) and the ability to pin individual channels to the sidebar.
What I have in mind is an option that lets you scroll through the recent content from a group of channels (ex. cooking, travel, self hosting, tech review, etc.)
Very cool! Have you explored running this on an Android TV at all, since that’s what I was thinking of trying this on. That way you can flip through channels without needing to deal with login on TVs. Also I don’t think YouTube supports making feeds for channel types (ex. Cooking etc.), whereas an RSS feed would make it possible
The GoodKarmaToolkit in particular is an extra project that is managed by ArchiveBox, but the listed services aren’t made by them. I’m not as familiar with ArchiveBox itself, and it looks like there’s an open issue about AI stuff: https://github.com/ArchiveBox/ArchiveBox/issues/1139
Yup, Hoarder was the one I was planning to use for bookmark management: https://hoarder.app/