Yes, it plays a role. What exactly it’s doing is unclear, and it’s probably more that it’s setting up tau to do the real nasty stuff, but it contributes. We know that from experimental work in nonhuman animal models and converging longitudinal work in humans. See, for example: https://www.cell.com/neuron/pdfExtended/S0896-6273(22)00305-1
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That’s just *56. Amyloid has been known for decades to play some role, even though *56’s data was fraudulent (for a lay-friendly discussion, see https://www.alzheimers.org.uk/what-we-do/researchers/news/explaining-amyloid-research-study-controversy). Amyloid is certainly not the only thing at play, but it does play some role.
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Science@mander.xyz•Giving men a common antidepressant could help tackle domestic violence: world-first study
5·1 month agoI can find no evidence that it is permanent; stopping the drug should return most folks to normal.
Most, but not all: https://link.springer.com/article/10.1186/s12991-023-00447-0
That went right over my head. I figured zog was a typo lol. Thanks!
I’d never heard of this. People are crazy lol
I’m naive. What’s the whistle there?
It’s a common general education requirement for college in the US, yeah. Biology, physics, psychology, economics, English/writing, math, etc. are often all required, or at least a selection of most of the discipline-intro-level courses is.
Blue light is important for night vision, so either of those options would lead to less of an ability to see well after sunset.
No, glia support neurons; they do things like redirecting blood flow to more-active-than-usual neurons, mylenate axons, etc. They wouldn’t form a mesh around neurons’ photoreceptors the same way they do neurons’ somas and axons. What the article describes is that glia actually are critical at allowing for color vision during the day and night vision at night, since on land we’d get too much blue light to see color with much fidelity were it not for glia, and a similar filtration process helps us see at night. It’s not that it’s not as bad as it could be, it’s actually that vision is better this way (barring one small blind spot outside of our fovea–which, being outside of the fovea, would have low acuity anyways).
This arrangement actually optimizes color vision in the daytime and night vision at night. Evolution selected for the correct arrangement for those of us living on land:
https://theconversation.com/look-your-eyes-are-wired-backwards-heres-why-38319
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Programmer Humor@programming.dev•Everyone knows what an email address is, right? (Quiz)
49·5 months agoWhat if we 👉@👈 …? 🤭
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Ask Lemmy@lemmy.world•Is it normal to not be able to remember anything during burnout?
2·5 months agoI didn’t struggle with any of it when I went through it, I just have subsequently found that I didn’t retain many of the rules. The derivative’s power rule is about the only rule I don’t have to look up these days. I’d like an online resource that has a bunch of practice exercises to help drill that stuff into me.
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Ask Lemmy@lemmy.world•Is it normal to not be able to remember anything during burnout?
2·5 months agoCan you link me some? I’d honestly really appreciate it. I’ve used Khan academy but it was too sparse on exercises
Edit: spelling
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Ask Lemmy@lemmy.world•Is it normal to not be able to remember anything during burnout?
3·5 months agoFor learning calculus?
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Autism@lemmy.world•I'm an undiagnosed, presumably autistic person. Pretending to be one makes me feel comfy womfy.
7·6 months agoNo:
https://onlinelibrary.wiley.com/doi/full/10.1155/2021/9974791
Results indicate no association between RAADS‐R scores and clinical diagnostic outcome, suggesting the RAADS‐R is not an effective screening tool for identifying service users most likely to receive an ASD diagnosis.
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Open Source@lemmy.ml•Danish Ministry switching from Microsoft Office/365 to LibreOffice - The Document Foundation Blog
8·6 months agoReposts are better than no posts. Plus, plenty of people could have missed the original.
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Science Memes@mander.xyz•you miss all the shots you don't takeEnglish
1·6 months agoMy merit review this year specifically noted my high volume of peer review for why I exceeded expectations in the 20% service part of my contract. Again I say, faculty are remunerated for peer review. It’s better to do peer review for the service part of my contract than it is to sit on faculty senate. Doing peer review helps my research. It’s a win-win, unless I don’t want to get my full merit raise because i ignored service.
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Science Memes@mander.xyz•you miss all the shots you don't takeEnglish
6·6 months agoFaculty are paid for doing peer review just like we’re paid for publishing. We’re not paid directly for each of either, but both publishing (research) and peer review (service to the field) are stipulated within our contracts. Arxiv is also free to upload to and isn’t a journal with publication fees.




Recently, a company called Pangram appears to have finally made a breakthrough in this. Some studies by unaffiliated faculty (e.g., at U Chicago) have replicated its claimed false positive and false negative rates. Anecdotally, it’s the only AI detector I’ve ever run my papers through that hasn’t said my papers are written by AI.